BDBM17289 (1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one::CHEMBL1405::Estrone::Estrone (E1)::Estrone, 15::Estrovarin::Kestrone::Theelin::Unigen::[2,4,6,7-3H]-E1::[2,4,6,7-3H]-Estrone::folliculin
SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
InChI Key InChIKey=DNXHEGUUPJUMQT-CBZIJGRNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 17289
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of (unknown origin) 17beta-HSD1 assessed as conversion of [14C]estradiol to [14C]estrone using NADP+More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataKi: 9.50E+3nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of (unknown origin) 17beta-HSD1 expressed in HEK 293 cells assessed as conversion of [14C]estrone to [14C]estradiol using NADHMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of (unknown origin) 17beta-HSD1 expressed in HEK 293 cells assessed as conversion of [14C]estrone to [14C]estradiolMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of 17-beta HSD1 in T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataIC50: 218nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]-estrone into [14C]estrogenMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Chuq-Pavillon Chul And Université
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of His-tagged human 17beta-HSD1 expressed in Escherichia coli by scintillation countingMore data for this Ligand-Target Pair